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2nd Act Podcast

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Dec 18, 2018

Part 1

CBD episode

  • CBD serves as an antagonist to CB receptor agonists
    • In other words, CBD “mutes” the effects of the CB1 or CB2 receptors
  • CBD can elongate the “effect” of THC by inhibiting the cytochrome p450 enzymes
  • Also an antagonist to the GPR55 CBD molecule found in the caudate nucleus section of the brain
  • Because CBD cream does not attach to the CB1 or CB2 receptors, it's not addictive or habit forming
  • CBD acts as an agonist for the 5-HT 1A receptor (for anti-depressant, anti-anxiety effects)
  • CBD is an allosteric modulator of your opioid receptors for pain and chronic inflammation reduction
    • Hormonal:
      • CBD oil Reduces susceptibility to stress in HPA axis
      • The pancreas secretes glucagon and insulin
      • THC increases glucagon levels; CBD lowers insulin levels
      • Lower rates of obesity and Type 2 diabetes among CBD users
    • CBD oilHas been shown to modulate acute and chronic inflammation
    • CBD is an excellent recovery compound (but not immediately after working out)
    • How it affects insomnia:
      • Cannabidiol activates the same adenosine receptors as caffeine
      • CBD softgels can enhance or help sleep if caffeine is not present
        • Third party test reports are made available; a CBD company doing things the right way isn't afraid of transparency
        • 3 main ways to extract CBD at the moment:
        • Ethanol is Taylor's preferred method for CBD product extraction
          • Blended with coconut oil; some oil emulsions for topical use

This is a first for us! We interviewed Dr. Mike Leez a CBD expert on the results of his study for weight loss using cbd - before he had even released the results to the public! Yes, we got the scoop on the study he completed, what he's doing for his next CBD oil study and possibilities for what's coming up after that. Additionally, we talked about liposomal hemp; what cbd, green tea, turmeric and ginger have in common; and some really great science around the cannabinoids.


Part 2

Michael Chiarelli an entrepreneur, father, motivational speaker, race car driver, musician and chef! Michael has found the key to weightless and changed his lifestyle in honor of his late parents and a wish they made on their death beds. Listen to his extraordinary story and be inspired!!!! Helpful weightless tricks are also mentioned!!!


Justin Sims sits down with Janine Stella, Allie Severino and Sam Rae ( behind the camera) and talks about divorce, the excitement to Janine's new life and crazy adventures as she finds herself again

 Helpful resources

Toronto Canada based podcast featuring interviews with alternative medicine doctors

millenial magazine CBD podcast review

International association of functional medicine practitioners and related healthcare industry figures

Fitness and technology blog reviews products that mix the two methods

 Blog features trainers and physical therapy experts giving tips and advice

podcast featuring owner of empty vase flowers empire

 University of Connecticut blog that interviews science educators

 Maryland college student blog with opinions and results of medical and health related research

Veterans association blog with health and medical advice and news

 Green Bay Wisconsin based podcast features sports medicine doctors giving surgery tips for sports injuries

 Mindfulness podcast produced by indian guru

millenial magazine episode featuring benefits of CBD